Copy Number Variation (CNV) and
Comparative Genome Hybridization
Array-based methods used for copy number variation (CNV) analysis range from applications using tiling and BAC microarrays for array-based comparative genome hybridization (aCGH) analysis, to those that use commercially available SNP genotyping arrays. In fact, some SNP genotyping arrays specifically include probes designed to target known CNV hotspots to further aid in CNV analyses. A nice overview on the various microarray methods and strategies currently in use can be found here.
The Genomics Resource provides a number of options for those looking to perform CNV analysis.
- Tiling Microarrays
- SNP Genotyping Microarrays
- BAC Microarrays
Each researcher is responsible for purchasing all commercial arrays directly from the vendor. There are various levels of services provide which differ based on the platform selected. For more information on CNV analysis at FHCRC and available service options, please contact: Jeff Delrow (jdelrow@fhcrc.org, 206.667.2763) or Cassie Sather (csather@fhcrc.org, 206.667.2757).
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