Developmental Research Program

Program Director: Peter Nelson, M.D.; Co-directors: Janet Stanford, Ph.D., Paul Lange, M.D.

During the course of our initial SPORE grant, policies and procedures were developed for establishing a Developmental Research Program, which has been a successful component of our SPORE and continues with our 2006 renewal. On an annual basis, the program solicits innovative translational research projects in all areas of prostate cancer aimed at improving outcomes in prostate-cancer patients, and funds from three to five projects for a period of one year, with the option to extend funding for a second year if the research is successful and such an extension is justified. Applications are accepted from investigators within the SPORE participating institutions.

Goals: To fund innovative, translational research pilot projects (3-5 projects/year) aimed at improving the outcomes of prostate cancer patients.

Pilot Projects from Year 7:

• “Elucidation of novel mechanisms of sulphoraphane chemoprevention in a murine model”
  Joshi Alumkal, MD, Oregon Health & Science University
  
• “Novel ultra sensitive DNA-based cancer prostate biomarkers”
  Jason Bielas, PhD, Fred Hutchinson Cancer Research Center
  
• “Effect of dietary intervention on insulin and IGF-1 receptors in prostate cancer”
  Anne McTiernan, MD, PhD, Fred Hutchinson Cancer Research Center
  
• “Role of PACS-2 in prostate cancer”
  Gary Thomas, PhD, Oregon Health & Science University

	Previously Funded Projects
	Program Abstract
	Request for Applications (RFA)
	Publications