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A Randomized, Double-Blind and Placebo-Controlled Study of GS-1101 in Combination With Bendamustine and Rituximab for Previously Treated Chronic Lymphocytic Leukemia (CLL)

Complete title: A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Efficacy and Safety of GS-1101 (CAL-101) in Combination with Bendamustine and Rituximab for Previously Treated Chronic Lymphocytic Leukemia

Research Study Number       2597.00
    
Principal Investigator       John Pagel, MD, PhD
    
Phase       III

Look up trial at NIH

Research Study Description

The purpose of this study is to evaluate the effect of GS-1101 on the onset, magnitude, and duration of tumor control.

Eligibility Criteria (must meet the following to participate in this study)

Ages Eligible for Study: 18 Years and older

Genders Eligible for Study: Both

- Previously treated recurrent CLL

- Measurable lymphadenopathy

- Requires therapy for CLL

- Has experienced CLL progression <36 months since the completion of the last prior therapy

Other eligibility criteria may apply.

Exclusions (conditions that would prevent participation in this study)

- Recent history of a major non-CLL malignancy

- Evidence of an ongoing infection

- CLL refractory to bendamustine

- Concurrent participation in another therapeutic clinical trial

Other exclusion criteria may apply.



Research Study Number       2597.00
    
Contact       Seattle Cancer Care Alliance Intake Office
    
Telephone       800-804-8824 / 206-288-1024
    
   

Keywords
Chronic Lymphoid Leukemia (CLL); Hematologic Malignancies; Leukemia

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  • Whether you are eligible for a research study depends on many things. There are specific requirements to be in research studies. These requirements are different for each study.

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