Vaccine and Infectious Disease Division
Tuberculosis, caused by the bacterium Mycobacterium tuberculosis, remains one of the 3 most deadly infections globally. Current preventive (vaccine) and therapeutic (antibiotic) resources for tuberculosis exist, but have been inadequate to significantly reduce disease burden. Co-infection with HIV has increased the incidence of and mortality from both diseases and this interaction has spurred interest in implementation of integrated health care services. VIDD scientists are developing mathematical modeling tools in combination with clinical trial design for studying the effects of potential prevention and therapeutics on morbidity and mortality from tuberculosis.