PHS Program: Cancer Prevention Program
Research focus: Survivorship after cancer, clinical research related to stem cell transplantation, and statistical methodology for studies of diagnostic tests.
Additional Projects within Cancer Prevention:
The Childhood Cancer Survivor Study (CCSS) is a multi-institutional collaboration for which the coordinating center and PI (Dr. Les Robison) reside at St Jude Children's Research Hospital and the Statistical Center, headed by Dr. Leisenring, resides in the Cancer Prevention program at FHCRC. It is supported by a grant from the National Cancer Institute (U24 CA55727) of the National Institutes of Health and funds from ALSAC, a St. Jude fundraising organization.
CCSS has successfully established and followed 14,370 five-year survivors of childhood and adolescent cancer diagnosed between 1970-1986 and a sample of 3,737 sibling controls. The CCSS, derived through 26 participating clinical centers, has collected detailed information on cancer diagnosis, therapy received, and health and quality of life related outcomes.
The CCSS provides a dynamic framework and resource in which to investigate current and future questions regarding consequences of therapy, genetic associations, disease processes and causation, interventions, and quality of life among childhood cancer survivors.