At first, Sandra Seymour paid little attention to the tingling sensation in her toes. But when it became difficult to grip a frying pan while cooking breakfast for her children, she decided her odd symptoms warranted a visit to her doctor. There, Seymour learned the startling news that she had an autoimmune disease called scleroderma.

Like other autoimmune diseases, scleroderma results from an immune system that turns against the body's healthy tissue. In Seymour's case, which eventually progressed to a more severe form known as systemic sclerosis, the disease attacked her skin, joints and later, her lungs.

To read on, see this issue's cover story.

	From the Director
	"The Most Satisfying Thing I Do"
	When the Body Attacks Itself
	Partner Spotlight
	Research Spotlight
	Research Notes
	Partners in Research
	Events Roundup
	Credits